Five miles above the earth, an elite team of six men must make an air to air transfer, in order to save 400 lives on board a 747...and 40 million below.

Terrorists hijack a 747 inbound to Washington D.C., demanding the release of their imprisoned leader. Intelligence expert David Grant (Kurt Russell) suspects another reason and he is soon the reluctant member of a special assault team that is assigned to intercept the plane and hijackers.