World War II had finished, but it left indelible marks.

In 1945 Germany, following the end of World War II, Leopold Kessler, an American of German descent, is hired by his uncle as a sleeping car conductor on the Zentropa train line. Leopold's wish is to be neutral to the ongoing purges of loyalists by Allied forces and do what he can to help a hurting country, but ultimately finds himself being used by both sides.