"Jaiphisut" follows the romantic journey of "Captain Ronajak Juthathep", a charismatic police officer, who cross paths with "Jaiphisuat", or "Noo Phook", a sweet yet strong-willed school teacher. In their childhood, "Noo Phook" was a chubby girl whom "Ronajak" loved to tease, creating a lasting grudge that makes her initially distrust and avoid him when they reunite as adults. However, fate forces them together when "Ronajak" becomes the guardian of "Somjeed", an orphaned girl who happens to be Noo Phook’s student. As their shared responsibilities ignite a deeper affection, they must navigate a major obstacle regarding Jaiphisuat’s mysterious past.